PR Interval on ECG – Measurement and Clinical Significance
How to Measure PR Interval on ECG?
Definition:
PR interval is measured from the beginning of the P wave to the beginning of the QRS complex.
Step-by-step method:
1. Use Lead II (usually best P wave visibility).
2. Identify:
Onset of P wave
Onset of QRS complex (first deflection – Q or R)
3. Count small boxes between them.
ECG Paper Speed: 25 mm/s
1 small box = 0.04 sec (40 ms)
1 large box = 0.20 sec (200 ms)
Normal PR interval:
120–200 ms
(3–5 small boxes)
Measure in multiple beats and take the average if rhythm is irregular.
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What Does PR Interval Represent?
Atrial depolarization
AV nodal conduction
His bundle conduction
It reflects AV nodal delay.
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PR Interval Abnormalities
1. Prolonged PR Interval (>200 ms)
Diagnosis: First-degree AV block
Causes:
Increased vagal tone
Drugs (β-blockers, CCBs, digoxin)
Ischemia (especially inferior MI)
Myocarditis
Electrolyte imbalance
Clinical significance:
Usually benign
May progress in structural heart disease
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2. Progressive PR Prolongation
Diagnosis: Second-degree AV block – Mobitz I (Wenckebach)
Features:
Gradually increasing PR
Dropped QRS
Cycle repeats
Common in:
Inferior MI
High vagal tone
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3. Fixed PR with Dropped Beats
Diagnosis: Mobitz II
Features:
Constant PR
Sudden dropped QRS
Significance:
Pathologic (infranodal disease)
Risk of complete heart block
Requires pacing
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4. Short PR Interval (<120 ms)
Causes:
Pre-excitation syndromes
Wolff-Parkinson-White syndrome (short PR + delta wave + wide QRS)
Junctional rhythm (P wave absent or retrograde)
Clinical importance:
Risk of SVT
Risk of AF with rapid conduction (WPW)
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5. Variable PR Interval
Seen in:
Atrial fibrillation (no true PR measurable)
Wandering atrial pacemaker
AV dissociation
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Quick Exam Points
Normal PR: 120–200 ms
> 200 ms → First-degree AV block
<120 ms → Pre-excitation
Progressive prolongation → Mobitz I
Fixed PR with dropped beat → Mobitz II

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